Read the recent review by Alexandra Navarro and Mary Ann Collins in the February, 2016 issue of Cytoskeleton about the role of the nucleus as a mechanosensing organelle. Navarro AP, Collins MA, Folker ES. The nucleus is a conserved mechanosensation and mechanoresponse organelle. Cytoskeleton. 2016 Feb;73(2):59-67. DOI: 10.1002/cm.21277